Our fastest disintegrating ODT

Differentiate a product, extend a patent and gain a marketing advantage. Lyoc makes your medication easy and convenient for patients to take. Taste-masking and flavoring make the experience more pleasant for patients, which can lead to greater patient preference for your product.

Placed in the mouth, Lyoc will disintegrate rapidly without water. As the tablet disintegrates, drug microparticles are released and swallowed as a slurry or suspension. Complete dissolution and systemic absorption occur in the GI tract. Lyoc pharmacokinetics can be matched to the conventional dosage form.

Deliver your drug faster – disintegrates in seconds

Lyoc technology lyophilizes, or “freeze-dries” an aqueous solution, suspension, or emulsion of an API and excipients. Lyoc’s high degree of porosity yields shorter disintegration times than compressed tablets.

The Lyoc manufacturing process produces a stable product without use of additives, preservatives or gelatins. This process is environmentally friendly and cost-effective because it doesn’t require organic solvents.

Lyoc technology is compatible with CIMA taste-masking techniques, customized release, high dosing and fixed-dose combination products.

Quick facts:

  • Oral administration, GI tract absorption
  • Dose range: 500 mcg – 500 mg
  • Disintegration time: 2-20 seconds
  • Tablet size: 3/8” - 5/8”
  • Customized release profiles (IR, SR,MR and enteric-coated)
  • Bitter drugs can be taste-masked
  • Flavor, color and debossing options to match your brand identity
  • The moisture stability of Lyoc allows for use of conventional packaging materials
  • Child-resistant packaging options

All globally acceptable ingredients:

  • Filler
  • Binder, no gelatin
  • Flavor
  • Sweetener
  • Surfactant
  • Suspending agent

Successfully commercialized in over 20 countries

Seven products utilizing Lyoc technology have been commercialized in more than 20 countries. Product examples include:

  • Spasfon-Lyoc® (phloroglucinol)
  • Proxalyoc® (piroxicam)
  • Paralyoc® (acetaminophen)
  • Loperamide-Lyoc® (loperamide)

Overview

Our fastest disintegrating ODT

Differentiate a product, extend a patent and gain a marketing advantage. Lyoc makes your medication easy and convenient for patients to take. Taste-masking and flavoring make the experience more pleasant for patients, which can lead to greater patient preference for your product.

Placed in the mouth, Lyoc will disintegrate rapidly without water. As the tablet disintegrates, drug microparticles are released and swallowed as a slurry or suspension. Complete dissolution and systemic absorption occur in the GI tract. Lyoc pharmacokinetics can be matched to the conventional dosage form.

Technical Notes

Deliver your drug faster – disintegrates in seconds

Lyoc technology lyophilizes, or “freeze-dries” an aqueous solution, suspension, or emulsion of an API and excipients. Lyoc’s high degree of porosity yields shorter disintegration times than compressed tablets.

The Lyoc manufacturing process produces a stable product without use of additives, preservatives or gelatins. This process is environmentally friendly and cost-effective because it doesn’t require organic solvents.

Lyoc technology is compatible with CIMA taste-masking techniques, customized release, high dosing and fixed-dose combination products.

Quick facts:

  • Oral administration, GI tract absorption
  • Dose range: 500 mcg – 500 mg
  • Disintegration time: 2-20 seconds
  • Tablet size: 3/8” - 5/8”
  • Customized release profiles (IR, SR,MR and enteric-coated)
  • Bitter drugs can be taste-masked
  • Flavor, color and debossing options to match your brand identity
  • The moisture stability of Lyoc allows for use of conventional packaging materials
  • Child-resistant packaging options

All globally acceptable ingredients:

  • Filler
  • Binder, no gelatin
  • Flavor
  • Sweetener
  • Surfactant
  • Suspending agent

Case Study

Successfully commercialized in over 20 countries

Seven products utilizing Lyoc technology have been commercialized in more than 20 countries. Product examples include:

  • Spasfon-Lyoc® (phloroglucinol)
  • Proxalyoc® (piroxicam)
  • Paralyoc® (acetaminophen)
  • Loperamide-Lyoc® (loperamide)