High-dose oral formulations, conveniently packaged

Oral granules/powders can be dosed greater than one gram. Granules can be taste-masked, colored, flavored or formulated with a customized release profile. Size of granules is engineered to optimize mouthfeel.

Granules are conveniently packaged in individual portable sachets, which can be poured directly into the mouth or sprinkled on food.

A challenge with granular formulations can be the bitterness of the drug. CIMA overcomes the bitterness problem with taste-masking techniques that go beyond adding flavors and sweeteners. CIMA granules deliver a pleasant-tasting and easy-to-administer product, which can lead to better patient acceptance.

Option for higher doses

CIMA oral powder technology can accommodate doses higher than solid dosage forms        (>1 gram). The packaging sachet for the oral powder technology is unit-dose, moisture-impermeable, and has the flexibility to meet many child-resistant packaging requirements.

Overview

High-dose oral formulations, conveniently packaged

Oral granules/powders can be dosed greater than one gram. Granules can be taste-masked, colored, flavored or formulated with a customized release profile. Size of granules is engineered to optimize mouthfeel.

Granules are conveniently packaged in individual portable sachets, which can be poured directly into the mouth or sprinkled on food.

A challenge with granular formulations can be the bitterness of the drug. CIMA overcomes the bitterness problem with taste-masking techniques that go beyond adding flavors and sweeteners. CIMA granules deliver a pleasant-tasting and easy-to-administer product, which can lead to better patient acceptance.

Technical Notes

Option for higher doses

CIMA oral powder technology can accommodate doses higher than solid dosage forms        (>1 gram). The packaging sachet for the oral powder technology is unit-dose, moisture-impermeable, and has the flexibility to meet many child-resistant packaging requirements.

Case Study